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Gene set testing after dream analysis

zenith() performs gene set analysis on the result of differential expression using linear (mixed) modeling with dream by considering the correlation between gene expression traits. This package implements the camera method from the limma package proposed by Wu and Smyth (2012). zenith() is a simple extension of limma::camera() to be compatible with linear mixed models implemented in variancePartition::dream().

Install

# Install package and dependencies
devtools::install_github("DiseaseNeuroGenomics/zenith")

May 13, 2022